Signos
by Signos Inc.
One of the few CGM programs with an FDA clearance specifically for weight management, developed with researchers from four major universities.
✓ Last verified July 2026
What it is
A CGM-based weight-management platform, FDA-cleared for weight management specifically (not only diabetes), developed by researchers from Harvard, Cornell, Stanford, and Princeton. It combines real-time glucose feedback with AI-powered personalized guidance on food and movement, daily/weekly metabolism scores, and included registered-dietitian support, plus a 30-day results guarantee. The company reports 86% of members see success in their first month. $127/month, hardware (CGM) included in the membership cost — contrasted against a DIY CGM approach the company estimates at $800+/month. A separate GLP-1 Bundle option is also available. HSA/FSA eligible.
Key features
- FDA-cleared for weight management (not just diabetes)
- AI-powered personalized food/movement guidance
- Daily and weekly metabolism scores
- Included registered dietitian support
- 30-day results guarantee
Best for
People who want an FDA-cleared, CGM-based weight-management program with included dietitian support.
Pricing
$127/month, CGM hardware included in membership separate GLP-1 Bundle option available. No free tier or trial mentioned.
Integrations
- Apple Health
- Google Health Connect
- smartwatches
- smart scales
Useful for
Other cgm & metabolic programs
Combines CGM data specifically with GLP-1 dose-titration support and nationwide medication home delivery — a tighter medication+device integration than most CGM-only competitors.
Pulls in sleep, HRV, recovery, and strain data from Oura Ring/WHOOP alongside glucose readings, so the AI coaching accounts for recovery state, not just food and glucose.
Predicts a meal's blood-sugar impact before you eat it, rather than only reporting the response after the fact, and extends the same engine into clinician-facing tools.